Figure 1. Effect of AGE-BSA on cell morphology and RAGE expression of human periodontal ligament fibroblasts (PDL fibroblasts). Relative to control cells (C), 48-h treatment with AGE-BSA altered cell morphology and reduced the number of cells (A). BSA-treated cells (B) were similar to control cells (C). Similarly, immunocytochemistry indicated that cells treated with AGE-BSA for 48 h had significantly greater expression of RAGE (D) than BSA-treated cells (E) and control cells (F). Magnification, 400×.
