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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Kidney Int. 2013 Dec 4;85(3):611–623. doi: 10.1038/ki.2013.462

Figure 1. Effects of AMP-activated protein kinase (AMPK) activation on glomerular expansion from mice on standard diet (STD), high-fat diet (HFD), and HFD + AICAR.

Figure 1

Representative photomicrographs (original magnification ×400) illustrating glomerular pathological features with periodic acid–Schiff (PAS) staining in (a) STD, (b) HFD, and (c) HFD + AICAR mice. Quantitative analysis of (d) glomerular surface area and (e) glomerular matrix at week 14. Values are means ±s.e.m. N = 6 in each group. Statistical analyses were performed by one-way analysis of variance (ANOVA) followed by Newman–Keuls, *P ≤ 0.05 versus mice on STD and #P ≤ 0.05 versus mice on HFD. AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside.