Quantitative analysis of triglycerides, long-chain nonesterified fatty acid (NEFA), short-chain NEFA, cholesteryl esters, and phosphatidylcholine levels in liver (a, c, e, g, i, respectively) and in the kidney (b, d, f, h, j, respectively) in mice fed a standard diet (STD), a high-fat diet (HFD), or HFD + AICAR. Values are means ± s.e.m. N = 6 in each group. Statistical analyses were performed by one-way analysis of variance (ANOVA) followed by Newman-Keuls, *P ≤ 0.05 versus mice on STD and #P ≤ 0.05 versus mice on HFD. AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside.