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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Kidney Int. 2013 Dec 4;85(3):611–623. doi: 10.1038/ki.2013.462

Table 1.

Metabolic data of mice fed standard diet (STD), high-fat diet (HFD), or HFD + AICAR

STD HFD HFD + AICAR
Body weight, g 28.50 ± 0.64 45.30 ± 0.81* 34.00 ± 1.23#
Plasma glucose level,
Mg/dl
145.2 ± 5.1 187.0 ± 8.2* 148.3 ± 10.2#
Kidney weight, g 0.306 ± 0.007 0.353 ± 0.006* 0.318 ± 0.012#
Kidney weight, g/mm
of tibia length
0.0154 ± 0.0007 0.0174 ± 0.0003* 0.0159 ± 0.0004
Adiponectin, µg/ml 14.6 ± 2.9 18.2 ± 2.3 25.7 ± 2.1*#
Plasma insulin, ng/ml 0.50 ± 0.01 1.07 ± 0.20* 0.52 ± 0.03#
UACR, µg/mg 5.99 ± 1.40 79.80 ± 14.06* 21.66 ± 4.46#

Abbreviations: AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; UACR, urine albumin/creatinine ratio.

Statistical analyses were performed by one-way analysis of variance (ANOVA) followed by Newman–Keuls,

*

P ≤ 0.05 versus mice on STD and

#

P ≤ 0.05 versus mice on HFD.

Values are means ± s.e.m; n = 6 in each group.