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. 2014 Nov 11;2014:403970. doi: 10.1155/2014/403970

Figure 2.

Figure 2

Effect of 5-LO deficiency on the in vivo priming of bone-marrow precursors for increased response to IL-5 ex vivo. PAS and ALOX mice were sensitized with OVA and challenged i.p. Bone-marrow was collected 48 h after challenge and cultured. Data (mean + SEM) are the numbers of EPO+ cells produced in culture with IL-5, 1 ng/mL, for 7 days, from bone-marrow of the indicated experimental groups (n = 8). All significant differences are indicated.