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Iohexol resulted in a more significant reduction of renal function compared with iodixanol in 5/6 NE rats. Changes in the levels of (a) BP, (b) Scr, (c) BUN, and (d) Ccr before and at 24 h, 48 h, and 72 h after an intravenous injection of saline, iohexol, or iodixanol. ** P < 0.01 and * P < 0.05 versus the control group; n = 8.
