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. 2014 Nov 12;2014:402475. doi: 10.1155/2014/402475

Figure 2.

Figure 2

Clustering based on the global normalized Cqs of the 20 most differentially expressed microRNAs (a) and even clustering based on the raw NRQs of only the 10 most differentially expressed miRNAs (b) were performed. As demonstrated here, clustering can be archived that distinguishes Down syndrome from euploid pregnancies utilizing a subset of 10–20 miRNAs. Sample identification comprised of: sample ID number.fetal sex.week of gestation.group. Abbreviations: f = female, m = male, T = Trisomy 21, N = normal.