Table 1.

Desirable characteristics for real-time image guidance surgery

Characteristic	Description
Intraoperative	Hardware conducive to be used in the operating room, during surgery
Real-time	≥ 24p frames per second image acquisition and display to surgeon without latency
High specificity	Contrast agent that very specifically accumulates in the tumor being imaged. Low false negatives
High sensitivity	High detection sensitivity of imaging system Detection of low fluorescence signal and small tumors
High resolution	Detection of small tumors and interrogation of the tumor boundary
Wearable	Ergonomic, hands-free unrestrictive movement
Non-interfering	Information display in a form that does not distract surgeon from the surgical bed
User friendly	Requires minimal training and no specialized operators