Table 1. Effects of PL-ES or PL-I-ES on Caspase Activity.
Cancer cells (controls) | PL-ES (100 µg/mL) |
PL-I-ES (250 µg/mL) |
||
---|---|---|---|---|
Csp-3 | Csp-9 | Csp-3 | Csp-9 | |
PC-3 (1.0)a | 3.0 | 3.4 | 3.5 | 4.2 |
DU-145 (1.0)a | 3.5 | 4.4 | 1.2b | 1.3b |
LNCaP (1.0)a | 2.9 | 3.3 | 1.5b | 1.6b |
T24 (1.0)a | 3.3 | 4.2 | 3.2 | 3.9 |
ACHN (1.0)a | 2.6 | 3.0 | 1.1b | 1.3b |
A549 (1.0)a | 2.8 | 3.3 | 2.5 | 2.9 |
MCF-7 (1.0)a | 3.4 | 4.2 | 3.3 | 4.0 |
AGS (1.0)a | 2.9 | 3.2 | 2.9 | 3.5 |
HepG2 (1.0)a | 3.4 | 4.3 | 3.7 | 4.5 |
U-87 (1.0)a | 2.8 | 3.1 | 2.3 | 2.6 |
aA value of 1.0 in parenthesis indicates an arbitrary number set for activity of caspase-3 (Csp-3) and caspase-9 (Csp-9) in control or untreated cells, following the results of enzymatic assays. bP > 0.05 (differences are not significant compared to controls).