The scalable unit for building vascularized myocardial grafts meets several criteria including a slowly degrading, porous, structurally and mechanically anisotropic heart cell scaffold (2L BSoff APS, two tan colors), a rapidly degrading, porous vascular-parenchymal interface (sc-PGS PM, stippled grey, *), and a slowly degrading μfluidic base (APS, dark grey). These components are stacked pair-wise in a parallel configuration to produce either 4L or 8L devices. Inset 1 shows fabrication of the interface by sphere pore templating and spin coating. Inset 2 shows layer-by-layer fabrication of a 4L device.