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. 2014 Nov 26;9(11):e113539. doi: 10.1371/journal.pone.0113539

Table 4. Clinical characteristics of patients with invasive infection caused by K. pneumoniae/variicola .

All (n = 139) No. (%) KpI (n = 96) No. (%) KpIII (n = 34) No. (%) KpI vs. KpIII Significance P<0.05
Age, median, years 70 65.1 68 0.62
Male sex 87 (62.6) 58 (60.4) 26 (76.5) 0.093
Charlson index, median 2 (0–9) 2 (0–9) 3 (1–7) 0.37
Charlson index 0–1 18 (12.9) 17 (17.7) 1 (2.9) 0.07
Charlson index 2–3 76 (54.7) 47 (49.0) 23 (67.7)
Charlson index 4–5 15 (10.8) 10 (10.4) 5 (14.7)
Charlson index>5 30 (21.6) 22 (22.9) 5 (14.7)
Diabetes 24 (17.3) 15 (15.6) 7 (20.6) 0.51
Heart disease 38 (27.3) 25 (26.0) 11 (32.4) 0.48
Pulmonary disease 25 (18.0) 14 (14.6) 8 (23.5) 0.23
Kidney disease 25 (18.0) 17 (17.7) 5 (14.7) 0.69
Liver disease 22 (15.8) 16 (16.7) 6 (17.6) 0.90
CNS-disease 24 (17.3) 18 (18.8) 5 (14.7) 0.60
Intestinal disease 17 (12.2) 13 (13.5) 6 (17.6) 0.56
Malignancy, all 81 (58.3) 51 (53.1) 21 61.8) 0.38
Hematologic 26 (18.7) 16 (16.7) 8 (23.5) 0.38
Urogenital 25 (18.0) 18 (18.8) 5 (14.7) 0.60
Colorectal 11 (7.9) 7 (7.3) 4 (11.8) 0.48
Pulmonary 7 (5.0) 4 (4.2) 3 (8.8) 0.38
Bile/liver/pancreas 6 (4.3) 6 (6.3) 0 0.34
Miscellaneous 6 (4.3) 3 (3.1) 2 (5.9) 0.61
Metastasized 26 (18.7) 18 (18.8) 5 (14.7) 0.60
Prev. organ transplant 4 (2.9) 3 (3.1) 0 (0) 0.57
Neutropenia 24 (17.3) 14 (14.6) 7 (20.6) 0.42
Hospital-acquired infection 68 (48.9) 50 (52.1) 14 (41.2) 0.27
Urinary catheter 54 (38.8) 40 (41.7) 10 (29.4) 0.21
Central catheter 43 (30.9) 28 (29.2) 12 (35.3) 0.51
Source of infection
Urinary 59 (42.4) 42 (43.8) 12 (35.3) 0.39
Respiratory tract 8 (5.8) 6 (6.3) 2 (5.9) 1.00
Bile/liver 11 (7.9) 9 (9.4) 2 (5.9) 0.73
Gastrointestinal tract 9 (6.5) 4 (4.2) 5 (14.7) 0.052
Miscellaneous 14 (10.1) 11 (11.5) 2 (5.9) 0.51
Unknown 38 (27.3) 26 (27.1) 11 (32.4) 0.63
Polymicrobial (all) 34 (24.5) 21 (21.9) 11 (32.4) 0.22
 E. coli 15 (10.8) 9 (9.4) 5 (14.7) 0.52
 S. aureus 5 (3.6) 3 (3.1) 1 (2.9) 1.00
 Enterococcus spp 5 (3.6) 2 (2.1) 2 (5.9) 0.28