Table 4. Clinical characteristics of patients with invasive infection caused by K. pneumoniae/variicola .
All (n = 139) No. (%) | KpI (n = 96) No. (%) | KpIII (n = 34) No. (%) | KpI vs. KpIII Significance P<0.05 | |
Age, median, years | 70 | 65.1 | 68 | 0.62 |
Male sex | 87 (62.6) | 58 (60.4) | 26 (76.5) | 0.093 |
Charlson index, median | 2 (0–9) | 2 (0–9) | 3 (1–7) | 0.37 |
Charlson index 0–1 | 18 (12.9) | 17 (17.7) | 1 (2.9) | 0.07 |
Charlson index 2–3 | 76 (54.7) | 47 (49.0) | 23 (67.7) | |
Charlson index 4–5 | 15 (10.8) | 10 (10.4) | 5 (14.7) | |
Charlson index>5 | 30 (21.6) | 22 (22.9) | 5 (14.7) | |
Diabetes | 24 (17.3) | 15 (15.6) | 7 (20.6) | 0.51 |
Heart disease | 38 (27.3) | 25 (26.0) | 11 (32.4) | 0.48 |
Pulmonary disease | 25 (18.0) | 14 (14.6) | 8 (23.5) | 0.23 |
Kidney disease | 25 (18.0) | 17 (17.7) | 5 (14.7) | 0.69 |
Liver disease | 22 (15.8) | 16 (16.7) | 6 (17.6) | 0.90 |
CNS-disease | 24 (17.3) | 18 (18.8) | 5 (14.7) | 0.60 |
Intestinal disease | 17 (12.2) | 13 (13.5) | 6 (17.6) | 0.56 |
Malignancy, all | 81 (58.3) | 51 (53.1) | 21 61.8) | 0.38 |
Hematologic | 26 (18.7) | 16 (16.7) | 8 (23.5) | 0.38 |
Urogenital | 25 (18.0) | 18 (18.8) | 5 (14.7) | 0.60 |
Colorectal | 11 (7.9) | 7 (7.3) | 4 (11.8) | 0.48 |
Pulmonary | 7 (5.0) | 4 (4.2) | 3 (8.8) | 0.38 |
Bile/liver/pancreas | 6 (4.3) | 6 (6.3) | 0 | 0.34 |
Miscellaneous | 6 (4.3) | 3 (3.1) | 2 (5.9) | 0.61 |
Metastasized | 26 (18.7) | 18 (18.8) | 5 (14.7) | 0.60 |
Prev. organ transplant | 4 (2.9) | 3 (3.1) | 0 (0) | 0.57 |
Neutropenia | 24 (17.3) | 14 (14.6) | 7 (20.6) | 0.42 |
Hospital-acquired infection | 68 (48.9) | 50 (52.1) | 14 (41.2) | 0.27 |
Urinary catheter | 54 (38.8) | 40 (41.7) | 10 (29.4) | 0.21 |
Central catheter | 43 (30.9) | 28 (29.2) | 12 (35.3) | 0.51 |
Source of infection | ||||
Urinary | 59 (42.4) | 42 (43.8) | 12 (35.3) | 0.39 |
Respiratory tract | 8 (5.8) | 6 (6.3) | 2 (5.9) | 1.00 |
Bile/liver | 11 (7.9) | 9 (9.4) | 2 (5.9) | 0.73 |
Gastrointestinal tract | 9 (6.5) | 4 (4.2) | 5 (14.7) | 0.052 |
Miscellaneous | 14 (10.1) | 11 (11.5) | 2 (5.9) | 0.51 |
Unknown | 38 (27.3) | 26 (27.1) | 11 (32.4) | 0.63 |
Polymicrobial (all) | 34 (24.5) | 21 (21.9) | 11 (32.4) | 0.22 |
E. coli | 15 (10.8) | 9 (9.4) | 5 (14.7) | 0.52 |
S. aureus | 5 (3.6) | 3 (3.1) | 1 (2.9) | 1.00 |
Enterococcus spp | 5 (3.6) | 2 (2.1) | 2 (5.9) | 0.28 |