Figure 2.
Structure of cADO with stearate bound (PDB ID 4TW3). (A) Ribbon diagram of cADO with helices colored from the N-terminus: 1 (blue), 2 (cyan), 3 (cyan-green), 4 (green), 5 (yellow–green), 6 (yellow), 7 (orange), and 8 (red); the iron atoms are brown and stearate is shown in gray. (B) The region containing the surface of helices 6, 7, and 8 shows a narrow hydrophobic cavity that is devoid of crystallographically resolved water molecules; L194 is shown in stick form at the center of the hydrophobic cavity.