Figure 6. Kidney pathology scores from rabbits subjected to CIAKI.

Summary pathology scores were calculated as outlined in the methods. (A) Pathology scores for animals treated with increasing doses of CM. (B) Pathology scores for animals pretreated with sildenafil citrate (6.0 mg/kg; single dose or q8 h) prior to CM exposure (5.0 g I/kg). Values are presented as mean ± SEM; n = 3–5. * indicates p<0.05 vs. 2.5 g I/kg.