Figure 1. TIM-2 schematic, slightly modified from Maathuis et al., [42].

a) peristaltic compartments with a hollow membrane inside, b) pH sensor, c) NaOH secretion, d) dialysate system, e) level sensor, f) gaseous N₂ inlet, g) sampling port, h) gas outlet, i) test compound + SIEM feeding syringe, j) temperature sensor.