Table 4.
Prior identification of IBS (diagnostic or therapeutic codes) for cases of Crohn’s disease and UC and their matched controls with at least 10 years of follow-up
| Prior diagnosis of IBS | Crohn’s disease |
Controls |
UC |
Controls |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N = 1551 | % | 95% CIs | N = 15,072 | % | 95% CIs | N = 2327 | % | 95% CIs | N = 22,997 | % | 95% CIs | ||
| IBS from diagnostic or prescription codes only in those with >10 years follow-up. | Ever | 622 | 40.1 | 37.7, 42.5 | 1914 | 12.7 | 12.2, 13.2 | 704 | 30.3 | 28.4, 32.1 | 3018 | 13.1 | 12.7,13.6 |
| Never | 929 | 59.9 | 57.5, 62.3 | 13,158 | 87.3 | 86.8, 87.8 | 1623 | 69.7 | 67.9, 71.6 | 19,979 | 86.9 | 86.4,87.3 | |
| 0–3 months | 93 | 6.0 | 4.8, 7.2 | 31 | 0.2 | 0.1, 0.3 | 93 | 4.0 | 3.2, 4.8 | 35 | 0.2 | 0.1, 0.2 | |
| 3–6 months | 65 | 4.2 | 3.2, 5.2 | 31 | 0.2 | 0.1, 0.3 | 52 | 2.2 | 1.6, 2.8 | 60 | 0.3 | 0.2, 0.3 | |
| 6–9 months | 27 | 1.7 | 1.1, 2.4 | 40 | 0.3 | 0.2, 0.3 | 27 | 1.2 | 0.7, 1.6 | 43 | 0.2 | 0.1, 0.2 | |
| 9–12 months | 27 | 1.7 | 1.1, 2.4 | 37 | 0.2 | 0.2, 0.3 | 27 | 1.2 | 0.7, 1.6 | 46 | 0.2 | 0.1, 0.2 | |
| 1–2 years | 66 | 4.3 | 3.3, 5.3 | 133 | 0.9 | 0.7, 1.0 | 53 | 2.3 | 1.7, 2.9 | 185 | 0.8 | 0.7, 0.9 | |
| 2–3 years | 36 | 2.3 | 1.6, 3.1 | 121 | 0.8 | 0.7, 0.9 | 49 | 2.1 | 1.5, 2.7 | 205 | 0.9 | 0.8, 1.0 | |
| 3–4 years | 28 | 1.8 | 1.1, 2.5 | 139 | 0.9 | 0.7, 1.0 | 49 | 2.1 | 1.5, 2.7 | 188 | 0.8 | 0.7, 0.9 | |
| 4–5 years | 31 | 2.0 | 1.3, 2.7 | 130 | 0.9 | 0.7, 1.0 | 31 | 1.3 | 0.9, 1.8 | 203 | 0.9 | 0.8, 1.0 | |
| 5–6 years | 31 | 2.0 | 1.3, 2.7 | 132 | 0.9 | 0.7, 1.0 | 31 | 1.3 | 0.9, 1.8 | 212 | 0.9 | 0.8, 1.0 | |
| 6–7 years | 35 | 2.3 | 1.5, 3.0 | 125 | 0.8 | 0.7, 1.0 | 32 | 1.4 | 0.9, 1.8 | 190 | 0.8 | 0.7, 0.9 | |
| 7–8 years | 26 | 1.7 | 1.0, 2.3 | 105 | 0.7 | 0.6, 0.8 | 32 | 1.4 | 0.9, 1.8 | 179 | 0.8 | 0.7, 0.9 | |
| 8–9 years | 17 | 1.1 | 0.6, 1.6 | 125 | 0.8 | 0.7, 1.0 | 43 | 1.9 | 1.3, 2.4 | 217 | 0.9 | 0.8, 1.1 | |
| 9–10 years | 25 | 1.6 | 1.0, 2.2 | 109 | 0.7 | 0.6, 0.9 | 28 | 1.2 | 0.8, 1.6 | 175 | 0.8 | 0.6, 0.9 | |
| 10+ years | 115 | 7.4 | 6.1, 8.7 | 656 | 4.4 | 4.0, 4.7 | 157 | 6.8 | 5.8, 7.8 | 1080 | 4.7 | 4.4, 5.0 | |
IBS: irritable bowel syndrome; UC: ulcerative colitis; CI: confidence interval.