Skip to main content
. Author manuscript; available in PMC: 2015 Nov 25.
Published in final edited form as: Circulation. 2014 Oct 7;130(22):1936–1943. doi: 10.1161/CIRCULATIONAHA.114.011359

Figure 3.

Figure 3

Activation-Recovery Interval (ARI) Maps. A. Maps are shown in superior (top row) and inferior (bottom row) views for the patients of figure 2. ARI (surrogate for local APD) values were abnormally long (magenta and white regions) in all three LQTS patients compared to control. The maximum ARI value in LQTS was 450 ms compared to only 340 ms (green in the left most column) in control. The localized prolongation of APD resulted in large ARI differences in all three LQTS types. The solid yellow line (top panels) connects two closest neighboring EGMs (from site 1 and site 2) with maximum ΔARIc. In all three LQTS patients, ΔARIc (ARIc(1)-ARIc(2)) exceeded 100 ms (compared to normal ΔARIc of only 30 ms in the left most column). As a result, there was a steep gradient of repolarization ΔARIc/Δx across this region (indicated by black arrows) which was two orders of magnitude greater than control (Normal: 7 ms/cm, LQT1: 104 ms/cm, LQT2: 146 ms/cm, LQT3: 140 ms/cm). B. The ECGI-reconstructed EGMs depict the time instances of AT (black dots) and RT (pink dots). The corresponding ARI values (RT – AT) are indicated below.