Table 4.

Clinical features of patients with and without past history of methotrexate (MTX) use; values expressed as mean (SEM) unless otherwise specified

	Past MTX	No past MTX	P value
Number of patients	42	260
Visit age	37.2 (2.8)	44.5 (1.1)	0.02
Age of onset	29.7 (3.2)	38.4 (1.3)	0.02
Disease duration	7.6 (1.1)	6.2 (0.5)	0.32
MRSS, number scored	42	258
MRSS score	9.9 (1.5)	5.4 (0.3)	<0.0001
LoSCAT, number scored	36	205
mLoSSI	17.1 (3.7)	12.3 (1.4)	0.18
LoSDI	26.7 (3.3)	15.3 (1.0)	<0.0001
PGA-A	26.4 (4.6)	29.8 (2.2)	0.54
PGA-D	42.8 (4.4)	27.3 (1.4)	<0.0001
Active disease, n (%)	22 (61)	143 (70)	0.33
Functional Impairment, n (%)	23 (55)	44 (17)	<0.0001
Deep involvement, n (%)	30 (71)	125 (48)	0.007