Table 1. Differentially expressed genes changed in the same direction in skeletal muscle of both the black bear and the arctic ground squirrel during torpor of hibernation.
Gene Symbol |
Gene Name | Black Bear | Arctic Ground Squirrel |
||
---|---|---|---|---|---|
| |||||
P | Log2FC | P | Log2FC | ||
Translation (13 genes) | |||||
Eif3k | Eukaryotic translation initiation factor 3 subunit K |
0.006 | 0.995 | 0.012 | 0.630 |
Eif3m | Eukaryotic translation initiation factor 3 subunit M |
0.020 | 0.876 | 0.030 | 1.021 |
Fxr1 | Fragile X mental retardation syndrome- related protein 1 |
0.008 | 1.649 | <0.001 | 0.871 |
Rpl23 | 60S ribosomal protein L23 | 0.013 | 0.826 | <0.001 | 0.641 |
Rpl27 | 60S ribosomal protein L27 | 0.011 | 0.990 | 0.012 | 0.485 |
Rpl27a | 60S ribosomal protein L27a | 0.012 | 0.931 | <0.001 | 0.619 |
Rpl8 | 60S ribosomal protein L8 | 0.021 | 0.389 | 0.005 | 1.354 |
Rps12 | 40S ribosomal protein S12 | 0.008 | 1.534 | <0.001 | 0.767 |
Rps13 | 40S ribosomal protein S13 | 0.010 | 0.856 | 0.036 | 0.335 |
Rps15a | 40S ribosomal protein S15a | 0.011 | 0.713 | <0.001 | 0.553 |
Rps23 | 40S ribosomal protein S23 | 0.008 | 1.099 | 0.004 | 0.630 |
Rps24 | 40S ribosomal protein S24 | 0.012 | 1.738 | 0.034 | 0.495 |
Rps27 | 40S ribosomal protein S27a | 0.008 | 1.592 | 0.003 | 0.831 |
Oxidation Reduction (7 genes) | |||||
Adh4 | Alcohol dehydrogenase 4 | 0.004 | −0.505 | 0.022 | −0.346 |
Aldh9a1 | 4-trimethylaminobutyraldehyde dehydrogenase |
0.032 | −1.538 | 0.015 | −0.706 |
Atp5f1 | ATP synthase subunit b, mitochondrial | 0.030 | −0.415 | 0.034 | −0.727 |
L2hgdh | L-2-hydroxyglutarate dehydrogenase, mitochondrial |
0.011 | −0.622 | 0.003 | −0.832 |
Ndufs1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
0.009 | −0.514 | 0.041 | −0.450 |
Nnt | NAD(P) transhydrogenase, mitochondrial | 0.007 | −0.756 | 0.007 | −0.873 |
Phyh | Phytanoyl-CoA dioxygenase, peroxisomal | <0.001 | −0.926 | <0.001 | −0.802 |
Other GO Categories (26 genes) | |||||
Acyp1 | Acylphosphatase | 0.014 | 0.794 | 0.002 | 0.827 |
Ankrd1 | Ankyrin repeat domain-containing protein 1 | 0.020 | 1.580 | 0.005 | 3.273 |
Atp6v0d1 | V-type proton ATPase subunit d 1 | 0.015 | 1.505 | 0.008 | 0.665 |
Caprin1 | Caprin-1 | 0.012 | 0.533 | 0.010 | 0.390 |
Cebpz | CCAAT/enhancer-binding protein zeta | 0.021 | 0.477 | 0.017 | 0.760 |
Cmya5 | Cardiomyopathy-associated protein 5 | 0.026 | 1.48 | 0.016 | 0.512 |
Gbe1 | 1,4-alpha-glucan-branching enzyme | 0.027 | 0.698 | 0.004 | 1.189 |
Gnb1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
0.040 | 0.598 | 0.042 | 0.347 |
Gnb2l1 | Guanine nucleotide-binding protein subunit beta-2-like 1 |
0.013 | 0.353 | <0.001 | 0.802 |
Maged2 | Melanoma antigen, family D, 2 | 0.016 | 0.293 | 0.008 | 0.460 |
Ndrg2 | NDRG family member 2 | <0.001 | 1.223 | <0.001 | 1.705 |
Nolc1 | Nucleolar and coiled-body phosphoprotein 1 | 0.026 | 0.466 | 0.035 | 0.518 |
Peal5 | Phosphoprotein enriched in astrocytes 15 | 0.029 | 0.342 | 0.014 | 1.202 |
Psmd13 | Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
0.012 | 0.570 | 0.047 | 0.609 |
Rb×1 | Ring-box 1, E3 ubiquitin protein ligase | 0.008 | 0.490 | 0.037 | 0.334 |
Sptbn1 | Spectrin, beta, non-erythrocytic 1 | 0.008 | 1.318 | 0.027 | 0.608 |
Tomm20 | Translocase of outer mitochondrial membrane 20 homolog (yeast) |
0.009 | 0.617 | 0.008 | 0.656 |
App | Amyloid beta (A4) precursor protein | 0.006 | −0.556 | 0.042 | −0.489 |
CdkS | Cyclin-dependent kinase 8 | 0.008 | −0.579 | 0.005 | −0.454 |
Ckm | Creatine kinase, muscle | 0.029 | −0.575 | 0.015 | −0.889 |
Coq10b | Coenzyme Q10 homolog B (S. cerevisiae) | 0.001 | −0.664 | 0.023 | −0.393 |
Dnm11 | Dynamin 1-like | 0.003 | −0.483 | 0.013 | −0.372 |
Kbtbd2 | Kelch repeat and BTB (POZ) domain containing 2 |
0.015 | −0.531 | 0.027 | −0.452 |
Pdlim7 | PDZand LIM domain 7 | 0.008 | −0.642 | 0.006 | −1.192 |
Tmeml26a | Transmembrane protein 126A | 0.001 | −0.436 | 0.004 | −0.671 |
Usp10 | Ubiquitin specific peptidase 10 | <0.001 | −0.805 | 0.001 | −0.364 |