Table 4.
Gene Set Enrichment Analysis (GSEA) results for selected pathways. NES - normalized enrichment score, positive values indicate elevated expression and negative - under-expression in torpid muscle, FDR false discovery rate. Significant values are in bold.
| Black Bear | Arctic Ground Squirrel | |||
|---|---|---|---|---|
| Pathway |
|
|||
| NES | FDR | NES | FDR | |
| Translation initiation | 2.49 | <0.001 | 1.77 | 0.008 |
| Translation elongation | 2.83 | <0.001 | 1.91 | <0.001 |
| Translation termination | 2.78 | <0.001 | 1.93 | <0.001 |
| Proteosome | −0.85 | 0.691 | 1.03 | 0.503 |
| Proteolysis | −1.08 | 0.321 | −0.86 | 0.674 |
| Lysosome | −0.90 | 0.619 | 1.10 | 0.289 |
| Ubiquitin proteosome | −1.31 | 0.065 | −0.81 | 0.709 |
| Muscle contraction | −1.61 | 0.016 | −1.61 | 0.014 |