Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Neurogastroenterol Motil. 2014 Oct 15;26(12):1717–1729. doi: 10.1111/nmo.12452

Figure 2. T3-SCI does not alter basic membrane properties or neuronal morphology of DMV neurons.

Figure 2

Representative traces illustrating the effects of T3-SCI on action potential properties. (A) DMV neurons were current clamped at −60mV prior to injection of a short (15ms) depolarizing current pulse of intensity sufficient to evoke the firing of a single action potential at current pulse offset. Note that T3-SCI had no effect on action potential duration or afterhyperpolarization amplitude or duration. (B) Control (left) and T3-SCI (right) neurons were current clamped at −60mV prior to injection of long (400ms) depolarizing current pulses of increasing magnitude. Note that the number of action potentials fired was unaffected by T3-SCI. (C) Graphical representation of the frequency of action potential firing (expressed as pulses per second, p.p.s.) in DMV neurons from control (black) and T3-SCI (red) DMV neurons. Note that T3-SCI did not have any significant effect upon the number of action potentials fired in DMV neurons. Representative computer-aided reconstructions of DMV neurons from control (D) and T3-SCI (E) brainstems reveals that T3-SCI did not alter the soma size or dendritic arborization of DMV neurons. Scale: 100μM in A & B.