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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Hepatology. 2014 Oct 29;60(6):1871–1878. doi: 10.1002/hep.27337

Table 2.

Number of cases, person-years, and incidence rates per 1,000 person-years in HCV patients with and without HBV co-infection by serum HBV DNA status

Clinical Outcome Infection Status Cases Person-Years Incidence Rate (95% CI) Unadjusted hazard ratio (95% CI)
Cirrhosis HCV mono-infected 11,369 652,344 17.43 (17.11 – 17.75) 1.00

HBV co-infected, DNA + 58 1,575 36.82 (28.46–47.62) 2.15 (1.66–2.79)
HBV co-infected, DNA − 55 2,571 21.39 (16.42–27.86) 1.22 (0.94–1.59)

HCC HCV mono-infected 2,613 717,052 3.64 (3.51 – 3.79) 1.00

HBV co-infected, DNA + 14 2,041 6.86 (4.06–11.58) 1.97 (1.16–3.33)
HBV co-infected, DNA − 15 2,895 5.18 (3.12–8.59) 1.38 (0.83–2.29)

Death HCV mono-infected 25,334 805,036 31.47 (31.08 – 31.86) 1.00

HBV co-infected, DNA + 95 2,277 41.72 (34.12–51.02) 1.37 (1.12–1.67)
HBV co-infected, DNA − 97 3,214 30.18 (24.73–36.82) 0.95 (0.77–1.15)