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. Author manuscript; available in PMC: 2015 May 23.
Published in final edited form as: Annu Rev Genet. 2014 Sep 18;48:457–484. doi: 10.1146/annurev-genet-120213-092033

Figure 5.

Figure 5

Emergent properties of the centromere. (Left) The yeast segregation apparatus, shown in the vertical position, serves as a model for multiple kinetochore-microtubule attachment-site centromeres found in other organisms. The kinetochore microtubules ( green) can be seen at the top and bottom, emanating from the spindle pole body (red ). The pericentromere DNA is organized as a network of loops ( yellow) radially arranged around the spindle axis. Cohesin (blue) and condensin ( purple) are enriched in the pericentromere and surround the central spindle. Abbreviations: LTR, long terminal repeat; MT, microtubule. Adapted from figure 6 in Reference 63.