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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Neurogastroenterol Motil. 2014 Oct 13;26(12):1730–1742. doi: 10.1111/nmo.12455

Fig 1.

Fig 1

Effect of dexamethasone (Dex) on post-inflammatory (post-TNBS) and non-inflammatory (AHS) colorectal hypersensitivity in the mouse. (A) Scatter plot showing colorectal sensitivity at 60 mmHg colorectal distension (CRD) measured on day 10 in individual mouse (% of maximum baseline responses). Note the outlier in the control group (in a dotted box). Excluding the outlier revealed significantly greater colorectal sensitivity in post-TNBS and AHS groups than in control (* p<0.05 by 1-way ANOVA). (B-D) Dex (5 mg kg-1), administered once daily for four days (days 11-14) did not alleviate colorectal hypersensitivity in any groups (before, day 10; after, day 15). Veh, saline vehicle. Mice with colorectal sensitivity greater than 125% (above shaded area) were considered hypersensitive to CRD.