Fig 6.
Colonic gene expression of transforming growth factor (TGF)-β cytokine family and their receptors. Gene expression of TGF-β1 (A) and TGF-β2 (B) was significantly lower in post-TNBS mice than in control or AHS-treated mice (** p<0.01 by 3-way ANOVA followed by Tukey's multiple comparison tests). (C) Gene expression of inhibin βA showed a tendency to a decrease in post-TNBS mice (p=0.074 vs. control). Its gene expression also tended to be higher in hypersensitive mice (p=0.056). (D) Gene expression of the mock receptor for TGF-β, BAMBI, tended to be higher in AHS-treated mice than in post-TNBS mice (p=0.07).