Table 1.

Genotype/allele frequencies of rs726344 and rs16835198 and binary logistic regression adjusted by sex in the Spanish cohort

	rs726344								rs16835198
		Controls		Cases						Controls		Cases
		N	%	N	%	OR	95%CI	P		N	%	N	%	OR	95%CI	P
Codom	GG	274	79.4	111	81.0	1.00		–	GG	163	47.4	58	42.3	1.00		0.48
	GA	64	19.0	26	19.0	1.19	0.69–2.06		GT	136	39.5	56	40.9	0.81	0.51–1.29
	AA	7	2.0	0	0.0	–	–		TT	45	13.1	23	16.8	0.71	0.38–1.33
Dom	GG	274	79.2	111	81.0	1.00		0.23	GG	163	47.4	58	42.3	1.00		0.25
	GA-AA	71	20.6	26	19.0	1.38	0.81–2.36		GT + TT	181	52.6	79	57.7	0.78	0.51–1.20
Reces	GG-GA	338	98.0	137	100.0	1.00		–	GG + GT	299	86.9	114	83.2	1.00		0.42
	AA	7	2.0	0	0	–	–		TT	45	13.1	23	16.8	0.78	0.43–1.41
Overdom	GG-AA	281	81.5	111	81.0	1.00		0.63	GG-TT	208	60.5	81	59.1	1.00		0.56
	GA	64	18.6	26	19.0	1.14	0.66–1.96		GT	136	39.5	56	40.9	0.88	0.57–1.36
Log-additive	–	–	–	–	–	1.52	0.94–2.48	0.08		–	–	–	–	0.83	0.62–1.12	0.23
Allele	G	612	88.7	248	90.5	1.00			G	462	67.2	172	62.8	1.00
	A	78	11.3	26	9.5	0.65	0.39–1.06	0.84	T	226	32.8	102	37.2	0.81	0.59–1.12	0.20

Codom codominant, Dom dominant, OR odds ratio, Overdom overdominant, Reces recessive;95 % CI 95 % confidence interval