Table 2.

Genotype/allele frequenciesof rs726344 and rs16835198 and binary logistic regression adjusted by sex in the Italian cohort

	rs726344								Irs16835198
		Controls		Cases						Controls		Cases
		N	%	N	%	OR	95%CI	P		N	%	N	%	OR	95%CI	P
Codom	GG	234	74.1	57	72.1	1.00		0.941	GG	104	32.9	31	39.2	1.00		0.569
	GA	78	24.7	21	26.6	0.88	0.50–1.55		GT	151	47.8	34	43.0	1.31	0.77–2.24
	AA	4	1.2	1	1.3	0.98	0.12–8.47		TT	61	19.3	14	17.8	1.27	0.66–2.64
Dom	GG	234	74.1	57	72.2	1.00		0.732	GG	104	32.9	31	39.2	1.00		0.288
	GA-AA	82	25.9	22	27.8	0.86	0.54–1.60		GT + TT	212	67.1	48	60.8	1.33	0.81–2.20
Reces	GG-GA	312	98.7	78	98.7	1.00		1	GG + GT	255	80.7	65	82.3	1.00		0.748
	AA	4	1.3	1	1.3	1.01	0.13–9.11		TT	61	19.3	14	17.7	1.12	0.61–2.11
Overdom	GG-AA	238	74.3	58	73.4	1.00		0.727	GG + TT	165	52.2	45	57.0	1.00		0.449
	GA	78	24.7	21	26.6	0.91	0.49–1.57		GT	151	47.8	34	43.0	1.22	0.71–2.01
Log-additive	–	–	–	–	–	0.84	0.61–1.78	0.814		–	–	–	–	1.16	0.87–1.98	0.378
Allele	G	546	86.4	135	85.4	1.00			G	359	56.8	96	60.8	1.00
	A	86	13.6	23	14.6	0.89	0.50–1.59	0.756	T	273	43.3	62	39.2	1.15	0.83–1.71	0.368

Codom codominant, Dom dominant, OR odd ratio, Overdom overdominant, Reces recessive, 95 % CI 95 % confidence interval