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Clear cell odontogenic carcinoma. a Aggressive tumor presenting as an ill-defined radiolucency of the mandible, b cross section of fresh resection specimen, c H&E, ×20; cords and nests of cell in a hyalinized stroma. Focal peripheral palisading is seen (arrow). d Fluorescence in situ hybridization dual-color break apart probe indicated the presence of EWSR1 (22q12) gene rearrangement in clear cell odontogenic carcinoma by the split red and green color signal
