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Properties of Three Backing Layers and Partition Coefficients of Donepezil from the Backing Layers to the Vehicle (n = 4, mean ± SD)
| Backing layer types | Component | MVTR (g/m2/24 h) | OT (cc/m2/24 h) | Partition coefficient |
|---|---|---|---|---|
| CotranTM 9700 | Polyurethane | 8,408 | NA | 0.29 ± 0.01 |
| CotranTM 9701 | Polyurethane | 709 | 4,858 | 0.40 ± 0.04 |
| CotranTM 9726 | Ethylene vinyl acetate | 12.8 | 6,650 | 0.00 ± 0.03 |
