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. 2014 Jun 25;15(6):1417–1428. doi: 10.1208/s12249-014-0166-z

Table I.

True Density, Bulk Density and Tapped Density (Mean ± SD, n = 3) of Granulated Lactose Carriers GL 212–250 μm, GL 250–300 μm, GL 300–425 μm and GL 425–600 μm, GL 600–850 μm and GL 850–1,000 μm. Bulk Density and Tapped Density Increased with Decreasing Particle Size of GLs

Pharmatose 100 M GL 212–250 μm GL 250–300 μm GL 300–425 μm GL 425–600 μm GL 600–850 μm GL 850–1,000 μm
True density (g/ml) 1.546 1.544 1.544 1.542 1.546 1.547 1.544
Bulk density (g/ml) 0.71 (0.02) 0.68 (0.01) 0.61 (0.01) 0.56 (0.00) 0.48 ± 0.00 0.45 ± 0.00 0.44 ± 0.01
Tapped density (g/ml) 0.94 (0.99) 0.82 (0.01) 0.71 (0.01) 0.65 (0.00) 0.58 ± 0.00 0.53 ± 0.03 0.48 ± 0.01
Carr’s Index (%) 23.82 (1.81) 16.66 (1.78) 14.12 (1.76) 14.23 (1.02) 15.97 ± 0.11 14.95 ± 3.57 9.50 ± 3.03
Angle of Repose (°) 37.2 (1.5) 31.1 (3.0) 30.2 (1.5) 32.0 (1.5) 30.0 ± 0.7 29.4 ± 0.0 27.3 ± 1.8