Table III.

Rate Constants of Aggregation of IFNβ-1b (1) at Different Inducing Temperatures and (2) in the Presence of Different Concentrations of Arginine; Calculations by the Best Fit of Experimental Data to Pre-nucleus Model Equation. R ² > 0.99 and χ ² < 0.0001

Entry		k*(min−1)	k n (M−1 min−1)	k −n (M−1 min−1)	k 1 (M−1 min−1)	k 2 (M−1 min−1)
1	4	7.5 ± 0.4 × 10−5	1.7 ± 0.8 × 10−8	3.5 ± 0.3 × 10−8	2.3 ± 1.1 × 10−9	2.5 ± 0.7 × 10−8
	25	3.5 ± 0.2 × 10−3	9.8 ± 1.9 × 10−7	8.8 ± 0.1 × 10−7	9.3 ± 0.7 × 10−8	7.7 ± 0.9 × 10−8
	37	5.4 ± 0.1 × 10−2	7.5 ± 0.4 × 10−7	4.1 ± 0.1 × 10−7	7.7 ± 0.8 × 10−8	7.5 ± 0.4 × 10−8
	70	1.1 ± 0.0 × 10−1	2.3 ± 0.6 × 10−7	1.1 ± 0.0 × 10−7	2.7 ± 0.2 × 10−7	7.7 ± 0.5 × 10−7
2	Control	8.8 ± 0.1 × 10−4	7.5 ± 1.0 × 10−6	2.1 ± 1.1 × 10−6	3.9 ± 0.5 × 10−8	3.5 ± 0.8 × 10−8
	Arginine 50 mM	1.8 ± 0.3 × 10−5	7.0 ± 0.9 × 10−7	8.1 ± 0.5 × 10−7	3.5 ± 0.7 × 10−8	1.1 ± 1.0 × 10−8
	Arginine 200 mM	5.3 ± 0.7 × 10−7	1.1 ± 0.9 × 10−7	2.1 ± 1.4 × 10−7	2.0 ± 0.5 × 10−8	3.5 ± 1.1 × 10−8
	Arginine 500 mM	4.3 ± 0.5 × 10−7	1.0 ± 0.8 × 10−7	1.2 ± 0.8 × 10−7	3.5 ± 0.9 × 10−8	2.9 ± 0.7 × 10−8

Mean ± SD, with two replicates