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Percent crystallinity of solid dispersions of acetazolamide with poloxamer-237 during initial characterization
| Sample | Parameter | ||
|---|---|---|---|
| ΔH m | ΔH m /ΔH m° | Percent crystallinity | |
| ACTL(1:1) | 121.54 | 0.2376 | 23.76% |
| ACTL(1:1.5) | 160.98 | 0.3147 | 31.47% |
| ΔH m°: 511.54 J/g | |||
| ΔH c: Nil | |||
ACTL: Solid dispersions of acetazolamide with poloxamer-237
ΔH m: Heat of melting of ACTL
ΔH c: Heat of cold crystallization of ACTL
ΔH m°: Heat of melting of pure drug
