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. 2014 Aug 20;15(6):1574–1587. doi: 10.1208/s12249-014-0182-z

Table IV.

IC50 Values for A549 Cells Exposed to Co-SD DPPC/DPPG Particles Containing PTX Versus Free PTX After 48 h of Exposure at 37°C

System composition (molar ratio) PTX IC50 (μM)
Free PTX 0.4174
25PTX:75DPPC/DPPG 0.0109
50PTX:50DPPC/DPPG 0.0266
75PTX:25DPPC/DPPG 0.0464

PTX paclitaxel, DPPC dipalmitoylphosphatidylcholine, DPPG dipalmitoylphosphatidylglycerol