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(A) Nitric oxide (NO) and (B) TNF-α production in RAW264.7 cells stimulated by 100 ng/mL of LPS in presence of berberine-free nanoparticles (NPs) and berberine-loaded nanoparticles (Ber-loaded NPs) by adding 30 μg/mL berberine equivalent of the nanoparticles to the apical and basolateral sides respectively (n = 5). ** p < 0.01 compared with the control; ## p < 0.01 compared with the LPS-treated group.
