Table 2.
Average 24 h, daytime and nocturnal ABP at baseline and the end of each phase (n = 37).
| Baseline | End of Active Phase | End of Placebo Phase | Difference (Active, Placebo) | ||
|---|---|---|---|---|---|
| Mean ± SD | Mean ± SEM | Mean ± SEM | Mean ± SEM | p | |
| 24-h ambulatory BP average | |||||
| SBP (mmHg) | 135.8 ± 9.8 | 134.6 ± 1.8 | 132.8 ± 1.5 | 1.78 ± 1.18 | 0.138 |
| DBP (mmHg) | 78.0 ± 6.3 | 79.7 ± 1.0 | 78.7 ± 0.9 | 1.05 ± 0.67 | 0.122 |
| MAP (mmHg) | 98.2 ± 7.0 | 97.7 ± 1.2 | 96.3 ± 1.0 | 1.32 ± 0.79 | 0.102 |
| HR (bpm) | 72.7 ± 8.2 | 72.4 ± 1.3 | 72.2 ± 1.3 | 0.24 ± 0.73 | 0.744 |
| Daytime BP average (07.00–22.00 h) | |||||
| SBP (mmHg) | 140.6 ± 9.7 | 139.4 ± 1.8 | 137.2 ± 1.4 | 2.11 ± 1.33 | 0.123 |
| DBP (mmHg) | 83.0 ± 6.5 | 82.8 ± 1.0 | 81.7 ± 1.0 | 1.16 ± 0.77 | 0.141 |
| MAP (mmHg) | 101.9 ± 7.10 | 101.4 ± 1.1 | 99.8 ± 1.0 | 1.60 ± 0.86 | 0.071 |
| HR (bpm) | 75.4 ± 8.3 | 75.2 ± 1.4 | 74.9 ± 1.4 | 0.30 ± 0.84 | 0.724 |
| Nocturnal BP average (22.00–07.00 h) | |||||
| SBP (mmHg) | 120.0 ± 11.7 | 119.6 ± 2.5 | 118.9 ± 2.1 | 0.68 ± 1.37 | 0.624 |
| DBP (mmHg) | 70.2 ± 7.3 | 70.0 ± 1.4 | 69.2 ± 1.3 | 0.76 ± 0.84 | 0.375 |
| MAP (mmHg) | 86.4 ± 8.4 | 86.2 ± 1.7 | 85.5 ± 1.4 | 0.73 ± 0.96 | 0.452 |
| HR (bpm) | 64.2 ± 9.0 | 64.0 ± 1.4 | 64.3 ± 1.2 | −0.32 ± 0.76 | 0.670 |