Table 3.
Multivariable cox proportional hazards models for the associations of HOUSES and educational level with two-year post-MI mortality.
Regression Models | HOUSES Index (Quartiles) | Education Level (4 Categories) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
(Hazard Ratio, 95%CI, p-Value) b | (Hazard Ratio, 95%CI, p-Value) b | |||||||||
4 (ref.) (highest SES) | 3 | 2 | 1 (lowest SES) | p a | 4 (ref) (highest SES) | 3 | 2 | 1 (lowest SES) | P a | |
Model 1 (unadjusted model) | 1 | 1.52 | 1.76 | 2.47 | <0.001 | 1 | 1.01 | 1.27 | 2.53 | <0.001 |
(0.85–2.73) | (1.01–3.06) | (1.46–4.19) | (0.59–1.72) | (0.79–2.03) | (1.55–4.14) | |||||
Model 2 | 1 | 1.37 | 1.27 | 1.86 | 0.036 | 1 | 0.95 | 1.16 | 1.84 | 0.015 |
(0.75–2.52) | (0.71–2.26) | (1.07–3.24) | (0.55–1.67) | (0.70–1.90) | (1.11–3.05) | |||||
Model 3 (full model) | 1 | 1.29 | 1.19 | 1.45 | 0.24 | 1 | 0.82 | 0.83 | 0.93 | 0.84 |
(0.68–2.43) | (0.65–2.16) | (0.82–2.58) | (0.46–1.44) | (0.51–1.37) | (0.55–1.57) |
Notes: a: p value is statistical significance for overall test (trend) for the association between socioeconomic status and MI mortality using Cochran-Armitage trend tests; b: Hazard ratio per an increment of strata of SES group; Model 1: univariate model only including SES variable as a predictor variable; Model 2: adjusted for all variables listed in Table 1 including sex, hypertension, hyperlipidemia, smoking, BMI, Killip class, STEMI, Anterior MI and ejection fraction, PTCA, CABG, statin, beta blocker and aspirin; Model 3: adjusted for age and Charlson Comorbidity Index in addition to all variables included in Model 2.