. 2015 Jan;37:124–133. doi: 10.1016/j.biomaterials.2014.10.028

Table 2.

Time-dependent changes of TNF-α and IL-6 secretion in 2D co-cultures.

	TNF-α		IL-6
	dTHP-1	dTHP-1/MSCs	MSCs	dTHP-1/MSCs
24 h	92.0 ± 15.6	78.2 ± 16.6	0.8 ± 0.2	10.7 ± 3.1^&
48 h	334.0 ± 32.2*	225.4 ± 39.6*^,&	1.2 ± 0.1*	56.8 ± 16.0*^,&
72 h	377.2 ± 64.4*	115.9 ± 23.0*^,&	1.4 ± 0.3*	77.7 ± 23.1*^,&
96 h	217.1 ± 27.6*	54.3 ± 6.4^&	1.4 ± 0.2*	98.3 ± 22.3*^,&

The data are expressed as pg of TNF-α and ng of IL-6 per ml of culture medium. Each value represents the mean ± SD of four independent experiments. *p < 0.05 compared to 24 h, ^&p < 0.05 compared to single-cultured cells.