Table 2.
Cost-effectiveness of an intervention continued for 5 years with the same intervention effectiveness in each quintile of deprivation.
|
Deprivation quintile |
|||||
|---|---|---|---|---|---|
| Least deprived | 2 | 3 | 4 | Most deprived | |
| Number entering intervention | 48 933 | 41 280 | 44 077 | 37 097 | 39 420 |
| Life years lived without disease (per 1000)a | 54.9 (17.5 to 93.5) | 58.7 (17.6 to 99.6) | 62.0 (19.5 to 105.9) | 69.6 (20.0 to 117.9) | 74.5 (22.8 to 128.0) |
| Life years lived with physical morbidity (per 1000)a | |||||
| Single condition | −43.0 (−78.6 to −8.9) | −45.1 (−81.9 to −8.1) | −47.7 (−86.6 to −9.5) | −52.5 (−93.9 to −9.6) | −54.4 (−101.8 to −9.0) |
| Dual conditions | −4.9 (−10.9 to 0.9) | −6.3 (−13.4 to0.95) | −6.2 (−13.4 to 0.6) | −7.5 (−15.8 to 0.95) | −8.9 (−19.4 to 1.60) |
| Triple conditions | −0.2 (−0.9 to 0.4) | −0.4 (−1.2 to 0.54) | −0.3 (−1.2 to 0.5) | −0.5 (−1.7 to 0.8) | −0.5 (−1.8 to 0.8) |
| Life years lived with depression (per 1000)a | −2.4 (−25.2 to 20.1) | −3.4 (−31.2 to 24.0) | −3.5 (−30.0 to 25.6) | −4.5 (−37.7 to 28.3) | −5.2 (−45.8 to 35.4) |
| Total intervention costs (£ per 1000) | 104 162 (104 144 to 104 179) | 105 929 (105 908 to 105 949) | 100 962 (100 941 to 100 983) | 97 547 (97 524 to 97 570) | 102 777 (102 750 to 102 803) |
| Incremental costs of non-intervention health-care utilization (£ per 1000) | −14 767 (−90 670 to 61 982) | −17 287 (−95 244 to 60 879) | −18 070 (−93 970 to 57 185) | −20 674 (−98 192 to 57 335) | −25 047 (−108 110 to 52 555) |
| Incremental total costs (£ per 1000)a | 89 394 (13 483 to 166 160) | 88 642 (10 680 to 166 791) | 82 892 (7172 to 158 163) | 76 873 (−649 to 77 965) | 77 730 (−5342 to 155 326) |
| Incremental QALYs (discounted 3.5%) (per 1000) | 3.73 (−10.05 to 18.30) | 4.09 (−11.6 to 20.2) | 4.45 (−11.7 to 29.7) | 4.7 (−12.7 to 21.0) | 6.1 (−10.2 to 22.9) |
| Incremental QALYs (discounted 1.5%) (per 1000) | 6.32 (−13.15 to 27.26) | 6.9 (−15.8 to 29.2) | 7.62 (−15.5 to 29.7) | 8.1 (−16.0 to 32.0) | 10.3 (−13.7 to 34.8) |
| Net Health Benefit (QALYs per 1000) | 0.75 (−13.32 to 15.38) | 1.13 (−14.7 to 17.8) | 1.69 (−14.7 to 17.3) | 2.11 (−15.7 to 18.8) | 3.5 (−13.3 to 20.6) |
| Probability cost-effective at £30 000 per QALY (%) | 52.5 | 54.0 | 58.0 | 58.8 | 63.3 |
Figures represent the mean (95% interval) for 2000 simulations, except where indicated.