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. 2014 Nov 27;8:411. doi: 10.3389/fnbeh.2014.00411

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Copyright © 2014 Bai, Yi, Liu, Wei and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flow chart for data analysis. To illustrate the procedure, we selected an arbitrary single channel to display. LFPs (band-pass filter: 0.3–300 Hz) were obtained from raw data via digital filters. Feature bands were further extracted according to the results of time-frequency spectral analysis. Spikes (band-pass filter: 250–7500 Hz) exceeding a preset voltage threshold were sampled at 30 kHz and were stored with time stamps. Then, entropy estimation of LFPs and spikes were performed. Finally, the correlation of spike entropy and LFP entropy was calculated to assess the spike-LFP coordination.