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. 2014 Sep 30;14(11):6590–6598. doi: 10.1021/nl503221p

Figure 4.

Figure 4

Cryo-TEM micrographs of genetically encoded asymmetric amphiphiles. (A–C) A160-(YGG)8, A160-(YG)8, and A160-Y8, respectively. (A) Constructs such as A160-(YGG)8 that do not self-assemble could not be visualized by cryo-TEM because of their high levels of hydration and low densities. (B,C) Changing the assembly domain from (YG)8 (B) to Y8 (C) causes a significant decrease in the length of the cylindrical micelles. (D–F) A160-(FGG)8 (D), A80-(FGG)8 (E), and A40-(FGG)8 (F) self-assemble into cylindrical micelles with similar aspect ratios. Scale bar represents 200 nm.