Figure 4. Early CD4+ T-cell rebound in the lung mucosa while sustained CD4+ T-cell depletion in the gut mucosal sites during SIV infection.
Flow cytometric analysis was performed for longitudinal assessment of CD4+ T-cell percentages from (A) BAL or (B) jejunum during early (first 24 days) and primary SIV infection (n=4 BAL, n=5 for jejunum, +/− standard error). (C) Flow cytometric analysis was performed to determine percentages of memory CD4+ T-cells (of total CD3+ T-cells) retained in the lung (total lung tissue), colon, and jejunum of macaques at 8-10 weeks post-infection and at 30 weeks post-infection (mean, +/− standard error, n=5).