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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Immunol. 2014 Mar 7;192(7):3308–3318. doi: 10.4049/jimmunol.1302415

Figure 6. Distinct innate anti-viral gene expression in the lung compared to gastrointestinal mucosa during chronic SIV infection.

Figure 6

(A) Changes in the expression of molecules associated with type I interferon (IFN) production (RIG-I, MDA-5), signaling (STAT1, STAT2) and response (OAS1, MX1) between healthy and chronically SIV infected animals was determined in the lung, colon and jejunum by DNA microarray analysis. (B) Comparison of the induction of type I IFN-stimulated retroviral restriction 26 factors, BST2/tetherin APOBEC3B, TRIM5, theta defensin-1, SAMHDI, and viperin in the lung, colon, and jejunum during chronic SIV infection. *p-value<0.05