FIGURE 3.

β-Apo-13-carotenone does not antagonize 9cRA-induced transactivation in cells expressing Gal4-DBD:RXRαLBD and an upstream activation sequence-driven luciferase reporter. Cells were incubated with 9cRA or β-apo-13-carotenone at concentrations of 0, 0.32, 1.6, 8, 40, 200, 1000, and 5000 nm for 24 h at 37°C (A); cells were incubated with these same concentrations of 9cRA in the presence or absence of fixed concentrations of β-apo-13-carotenone (B) or UVI3003 (C).