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Ribbon representative of Munc18-1 structure bound to syntaxin-1. Each domain of Munc18-1 is represented in a different color. Domain-1, -2, -3a, and -3b are shown in green, red, yellow, and cyan, respectively. Syntaxin-1 is represented in purple. On the right is an enlarged ribbon representative highlighting the domain-3a residues that have been mutated in the study as well as the interacting residues of syntaxin-1.
