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Schematic diagram depicting key features of the PAN locus and transcript. (A) The nucleotide numbering for the K7 ORF and PAN transcript corresponds to genbank accession number U75698.1 for HHV8/KSHV genome type M isolated from BC-1 cells. The numbering for the RRE within the PAN promoter and the ENE is from the transcription start site; (B) The secondary structure of the ENE and MRE sequence within PAN RNA to prevent degradation and increase stability.
