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Late posttraining activation of hippocampal D1/D5 receptors rescues the memory deficit caused by early blockade of D1/D5 receptors in mPFC. Animals were trained in IA with a strong footshock and immediately after that received bilateral intra-mPFC infusions of vehicle (VEH) or SCH23390 (SCH) plus bilateral intra-CA1 hippocampal infusions of VEH or SKF38393 (SKF) 12 h later. Memory retention was evaluated 7 days after training. *p < 0.05; TR, training.
