Table 3.
Effect of the triterpene on serum lipids and lipoproteins levels (mmol/L) in HFD-induced hyperlipidemia in rats
| Group | Total cholesterol | Triglyceride | VLDL-c | LDL-c | HDL-c |
|---|---|---|---|---|---|
| ND (after 21 days) | 1.38 ± 0.12 | 0.68 ± 0.11 | 0.14 ± 0.04 | 0.11 ± 0.04 | 1.14 ± 0.90 |
| (after 36 days) | 1.83 ± 0.24 | 0.79 ± 0.06 | 0.26 ± 0.18 | 0.10 ± 0.02 | 1.86 ± 0.07 |
| HFD (after 21 days) | 15.72 ± 1.10 | 1.29 ± 0.54 | 0.28 ± 0.22 | 7.41 ± 0.56** | 14.75 ± 0.19*** |
| (after 36 days) | 49.52 ± 4.83*** | 1.41 ± 0.35 | 0.28 ± 0.14 | 10.72 ± 0.94*** | 6.17 ± 0.16*** |
| HFD/KE1 (100 mg/kg) | 34.24 ± 1.50*** | 1.93 ± 0.15 | 0.39 ± 0.05 | 5.85 ± 0.81*** | 30.39 ± 0.92*** |
| HFD/KE1 (200 mg/kg) | 7.51 ± 0.97*** | 0.46 ± 0.05 | 0.09 ± 0.01 | 4.46 ± 0.82*** | 47.30 ± 0.9*** |
| HFD/lovastatin (10 mg/kg) | 38.66 ± 3.25* | 0.77 ± 0.13 | 0.15 ± 0.03 | 12.97 ± 0.59 | 29.13 ± 0.68*** |
All values are expressed as mean ± SEM, (n = 4); *p < 0.05, **p < 0.01 compared to the HFD 36 days; *p < 0.05, **p < 0.01, ***p < 0.001 compared to the ND 36 days.