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. 2014 Aug 8;2(8):e12092. doi: 10.14814/phy2.12092

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© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Effect of ionotropic glutamate receptor blockade in the NTS on the pattern of breathing and inspiratory drive in response to acute hypoxia in normoxic control (CON) versus chronically hypoxic (CSH) rats. Effects of chronic hypoxia and MK801 + DNQX on (A) inspiratory time (Ti), (B) expiratory time (Te), and (C) inspiratory drive (Vt/Ti) of CON and CSH rats before and after microinjection of drugs. Data are mean ± SEM from n =7 CON and 9 CSH rats. Asterisks (*) indicate significant (P < 0.05) difference between CON and CSH values. Daggers (†) indicate significant effect of drug relative to ACSF microinjection.