Figure 7.
Arterial blood gases are not changed by ionotropic glutamate receptor blockade in the NTS. (A) Average changes in Po2 and Pco2 in response to microinjection of MK801 + DNQX into the NTS of normoxic control (CON) and chronically hypoxic (CSH) rats breathing acute levels of 10% and 21% O2. (B) Average changes in arterial pH in response to microinjection of MK801 + DNQX into the NTS of CON and CSH rats breathing acute levels of 10% and 21% O2. All blood gases are corrected for body temperature. Numbers refer to the following: (1) normoxic rats breathing 21% O2; (2) normoxic rats breathing 10% O2; (3) chronically hypoxic rats breathing 10% O2; (4) chronically hypoxic rats breathing 21% O2. Data are mean ± SEM from n =3 rats per group.