Figure 3.

SDHC full-length and ASV mRNAs in HCT-15 cells treated with ROS reagents. To investigate mRNA dynamics following treatment with ROS reagents, quantification of SDHC mRNA was performed. mRNA expression levels are presented as the mRNA copy number per microgram of total RNA. ^*P<0.05 and ^**P<0.01, vs. untreated HCT-15 cells. SDHC, succinate dehydrogenase complex, subunit C; ASV, alternative splicing variants; ROS, reactive oxygen species; AAPH, 2,2′-azobis(2-amidinopropane) dihydrochloride; TTFA, thallium trifluoroacetate.