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. 2014 Nov 19;1(1):e000026. doi: 10.1136/lupus-2014-000026

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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Correlations between two measures of type I interferon activity and serum galectin-3-binding protein in the SLE-IFN-α (n=26) and HC-IFN-α (n=10) cohorts. (A) The IFN-α protein-activity scores obtained using the Mx-1 gene reporter assay and (B) the calculated IFN-α scores representing gene expression of IFN-inducible genes in PBMCs correlated significantly with serum concentrations of galectin-3-binding protein. Non-parametric correlation analysis (Spearman's r) was used to estimate correlations. IFN-α, interferon-α; HC, healthy controls; SLE, systemic lupus erythematosus; PBMCs, peripheral blood mononuclear cells.